| Pick | Team | Pos | Player | School |
| 1 | St. Louis Rams | QB | Sam Bradford | Oklahoma |
| | Ndamukong Suh is the higher rated player but the vibe from St. Louis is they want to get a franchise quarterback. Bradford has talent but the Rams will need to be patient with the former spread signal caller. The key to this pick will likely be Bradford's pro day performance. If healthy he goes #1 if not he falls. As an aside, one of the biggest surprises of the draft season is the lack of buzz surrounding Clausen esp. when compared to Bradford considering Clausen's pro style pedigree. |
| 2 | Detroit Lions | DT | Ndamukong Suh | Nebraska |
| | Buzz is building for the Lions to take left tackle Russell Okung (finally) but the one player who will change their mind is Suh. His ability to dominate on the defensive front would trump that option. If the Rams take Suh, Okung is the pick here. |
| 3 | Tampa Bay Buccaneers | DT | Gerald McCoy | Oklahoma |
| | If McCoy or Suh is on the board this is one of the easiest picks in the draft to predict. McCoy's ability to disrupt plays in the backfield would fill the defenses top need. |