| Pick | Team | Pos | Player | School |
| 1 | Miami Dolphins | OT | Jake Long | Michigan |
| The Dolphins take the safe route and take a left tackle to anchor their offensive line. Signability will be a major factor in this pick. |
| 2 | St. Louis Rams | DE | Chris Long | Virginia |
| Long is the pass rushing defensive end the Rams crave to play opposite Leonard Little. |
| 3 | Atlanta Falcons | DT | Glenn Dorsey | LSU |
| Passing on Matt Ryan is the smart move. Dorsey will anchor the Falcons defensive front and the team can find a QB with one of their 2nd round picks. |
| 4 | Oakland Raiders | RB | Darren McFadden | Arkansas |
| The Raiders select a playmaker to help take the pressure off quarterback JaMarcus Russell. Don't be surprised if Vernon Ghoston is the pick instead. |
| 5 | Kansas City Chiefs | OT | Ryan Clady | Boise St |
| The Chiefs reach a bit for Clady but taking a QB behind this offensive line would be a big mistake. |
| 6 | New York Jets | DE | Vernon Gholston | Ohio St |
| Gholston is the pass rushing OLB the Jets 3-4 defense needs. |
| 7 | New England Patriots | DE | Derrick Harvey | Florida |
| The Patriots are one of the hardest teams to figure out. CB is their biggest need but the Giants taught them the best pass defense is a pass rush. |
| 8 | Baltimore Ravens | QB | Matt Ryan | Boston College |
| The Ravens end Ryan's slide. Hopefully, Ryan can end the team's decade long search for a quarterback. |
| 9 | Cincinnati Bengals | DT | Sedrick Ellis | USC |
| The Bengals can only hope Ellis slides to them at #9. Ellis is not only a penetrating DT but a leader who could inspire a moribund defense. |
| 10 | New Orleans Saints | OLB | Keith Rivers | USC |
| The Saints are looking to get more athletic on defense and Rivers would be an excellent running mate for newly acquired LB Jonathan Vilma. |
| 11 | Buffalo Bills | CB | Leodis McKelvin | Troy |
| The Bills two biggest needs are WR and CB. CB is the best value here as there should still be quality receivers in round 2. |
| 12 | Denver Broncos | OT | Christopher Williams | Vanderbilt |
| Williams' athleticism should make him an excellent fit for the Broncos zone blocking scheme. |
| 13 | Carolina Panthers | G | Branden Albert | Virginia |
| The Panthers are looking to upgrade their O-line and Albert can step in right away at LG before moving to LT down the road. |
| 14 | Chicago Bears | RB | Rashard Mendenhall | Illinois |
| The Bears opt for a yet another first round running back. Is the 4th time a charm? |
| 15 | Detroit Lions | OT | Jeffrey Otah | Pitt |
| The Lions consider RB Jonathan Stewart, DE Philip Merling and OT Jeff Otah. Without improved blocking the ground and passing game don't have a chance. |
| 16 | Arizona Cardinals | CB | Dominique Rodgers-Cromartie | Tennessee State |
| DRC is the cornerback the Cardinals defense needs. |
| 17 | Minnesota Vikings | DE | Phillip Merling | Clemson |
| The Vikings benefit from Merling's hernia surgery as a top defensive end slides to #17. |
| 18 | Houston Texans | CB | Mike Jenkins | South Florida |
| The Texans consider Jonathan Stewart but with Dunta Robinson's injury they need a corner who can play right away. Jenkins fits the bill perfectly. |
| 19 | Philadelphia Eagles | RB | Jonathan Stewart | Oregon |
| Andy Reid & Co. surprise by going BPA and taking RB Jonathan Stewart. Not a popular pick for Eagles fans but Westbrook isn't getting any younger. |
| 20 | Tampa Bay Buccaneers | RB | Felix Jones | Arkansas |
| Cadillac Williams' injury has the Buccs in need of running back and Jones' ability to get outside is a nice fit for Gruden's offense. |
| 21 | Washington Redskins | WR | Limas Sweed | Texas |
| Sweed is the tall wide receiver the Redskins offense is looking for. |
| 22 | Dallas Cowboys | WR | Desean Jackson | Cal |
| The Cowboys take one out of the Patriot's book and draft a Wes Welker like slot receiver. Jackson's return abilities are a nice addition as well. |
| 23 | Pittsburgh Steelers | OT | Gosder Cherilus | Boston College |
| With the offensive tackles flying off the board, the Steelers make a bit of a reach selecting Cherilus out of BC. He should play right away at right tackle. |
| 24 | Tennessee Titans | WR | Devin Thomas | Michigan St |
| The Titans draft the wide receiver some are saying is the best in the draft. Vince Young will benefit from Thomas' size. |
| 25 | Seattle Seahawks | S | Kenny Phillips | Miami |
| The Seahawks fill a need for a ball hawking safety with Miami's Phillips. Seattle hopes he is the next in the long line of great Hurricane safeties. |
| 26 | Jacksonville Jaguars | DT | Trevor Laws | Notre Dame |
| With the top pass rushing defensive ends off the board, the Jags look to fill Marcus Stroud's shoes with energetic Trevor Laws. |
| 27 | San Diego Chargers | OT | Anthony Collins | Kansas |
| Without a 2nd or 3rd round pick the Chargers are primed to trade down. Staying at #28 they take the best right tackle on the board albeit a reach. |
| 28 | Dallas Cowboys | CB | Antoine Cason | Arizona |
| The Cowboys select a polished 4 year starter who should challenge Anthony Henry for a starting job from day one. |
| 29 | San Francisco 49ers | DE | Quentin Groves | Auburn |
| Groves is one of the draft's best 3-4 outside linebacker prospects and gives them the pass rusher on the edge their defense needs. |
| 30 | Green Bay Packers | CB | Aqib Talib | Kansas |
| The Packers debate Talib and Brandon Flowers to fill their corner need. Talib's return abilities and upside win out over the more polished Flowers. |
| 31 | New York Giants | S | Reggie Smith | Oklahoma |
| The Giants consider Dan Connor but decide the secondary needs help first. Smith's corner abilities are a plus but he likely steps in for Gibril Wilson at safety. |